Cognitive & Nootropics

Lion's mane, alpha-GPC, bacopa, ginkgo, and brain performance supplements.

Alpha-GPC

Alpha-GPC

Supports cognitive function in age-related decline, increases power output in athletes, and provides a highly bioavailable source of choline that crosses the blood-brain barrier.

Weak Evidence10 products
Lion's Mane Mushroom

Lion's Mane Mushroom

Cognitive support and neuroprotection through nerve growth factor (NGF) stimulation

Weak Evidence10 products
Magnesium L-Threonate

Magnesium L-Threonate

Brain magnesium levels, cognitive function, memory support

Weak Evidence10 products
Ginkgo Biloba

Ginkgo Biloba

Marketed for cognitive enhancement and dementia prevention, but the largest clinical trials have failed to support its most popular claims. Modest evidence exists for peripheral circulation and existing mild cognitive impairment.

Mixed Evidence10 products
Bacopa Monnieri

Bacopa Monnieri

Memory enhancement, particularly delayed recall and learning rate, with secondary benefits for attention and anxiety reduction

Mixed Evidence10 products
Acetyl-L-Carnitine

Acetyl-L-Carnitine

Diabetic peripheral neuropathy, cognitive aging support, mitochondrial energy in brain and nerve tissue

Mixed Evidence10 products
Citicoline

Citicoline

Attention, focus, age-related memory support, and cognitive recovery after ischemic insults

Mixed Evidence8 products
Phosphatidylserine

Phosphatidylserine

Modest support for age-related memory complaints; cortisol blunting in trained athletes at higher doses

Mixed Evidence9 products
Lemon Balm

Lemon Balm

Mild stress and anxiety reduction, sleep onset support, acute calmness and cognitive performance

Mixed Evidence7 products
Mucuna Pruriens

Mucuna Pruriens

Plant source of L-DOPA studied in Parkinson's disease; speculative use for mood, libido, and male fertility

Mixed Evidence10 products
Huperzine A

Huperzine A

Cognitive function in Alzheimer's disease and vascular dementia via reversible acetylcholinesterase inhibition

Mixed Evidence10 products
Agmatine Sulfate

Agmatine Sulfate

Sold heavily in pre-workouts for 'pumps' and as a neuropathic pain or mood aid; the marketing is far ahead of the human evidence on every one of those claims

Mixed Evidence8 products

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products discussed on this page are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before starting any supplement regimen.