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Pure Encapsulations vs Life Extension Vitamin D3 + K2 (2026)
Disclosure: We earn commissions on purchases made through our links. This never influences our scores. Editorial policy
The Verdict
Pure Encapsulations edges Life Extension on our rubric (92 vs 90 on our 0-100 execution score), helped by its Eurofins testing and clean hypoallergenic formulation. On cost the two are essentially tied - both run about $0.30-$0.31 per day. Pure Encapsulations gives you a focused D3 + MK-7; Life Extension gives you a broader D and K complex (MK-4, MK-7, and K1) plus iodine. In our view, choose Pure Encapsulations for a clean, focused formula, and Life Extension if you want the wider spread of K forms. Both are high-quality.
Pure Encapsulations Vitamin D3 + K2
Pure Encapsulations
Life Extension Vitamins D and K with Sea-Iodine
Life Extension
Head-to-Head Comparison
| Category | Pure Encapsulations Vitamin D3 + K2 Pure Encapsulations | Life Extension Vitamins D and K with Sea-Iodine Life Extension |
|---|---|---|
| Brand Score | 92/100Winner | 90/100 |
| Dosing & Form | 25/25Winner | 25/25 |
| Purity | 23/25Winner | 20/25 |
| Value | 19/25 | 22/25Winner |
| Transparency | 25/25Winner | 23/25 |
| Cost/Day | $0.30Winner | $0.31 |
| Dose/Serving | 4000IU | 5000IU |
| Form | cholecalciferol D3 + menaquinone-7 MK-7 | cholecalciferol D3 + MK-4 + MK-7 + K1 + iodine |
| Third-Party Tested | ✓ Yes | ✓ Yes |
| Proprietary Blend | No | No |
Why This Comparison Matters
Pure Encapsulations and Life Extension both make a combined D3 and K2 supplement, pairing vitamin D3 with vitamin K2 to support the way calcium is directed to bone rather than arteries. Pure Encapsulations uses D3 with MK-7 (the longer-lasting K2 form) at 4000 IU; Life Extension uses a broader D and K complex (MK-4, MK-7, K1) plus iodine at 5000 IU. This is the focused-versus-comprehensive D3+K2 decision.
Both are third-party tested. Pure Encapsulations is the hypoallergenic practitioner staple; Life Extension packs more forms of K into its formula. The right pick depends on whether you want a clean, focused D3+MK-7 or a broader multi-form K complex.
We scored both on evidence, quality, cost per day, and transparency.
Detailed Score Breakdown
Pure Encapsulations Vitamin D3 + K2
Pure Encapsulations
4,000 IU D3 + 100mcg MK-7 per capsule - both at solid, research-backed doses for bone and vascular support
Third-party tested by Eurofins/Silliker. Hypoallergenic. GMP+ certified. Best-in-class quality assurance.
$0.30/day from the 120-count bottle (4,000 IU D3 / 100mcg MK-7) - premium but reasonable for Pure Encapsulations quality
Exemplary label. Every ingredient listed. Hypoallergenic certified. Ideal for those with food sensitivities.
Optimal dosing for both components with best-in-class quality testing. The choice for those prioritizing quality, and after the 2026 repricing of the high-dose options it is also the cheaper per-day pick at full K2.
Life Extension Vitamins D and K with Sea-Iodine
Life Extension
5,000 IU D3 + 2,100mcg vitamin K (MK-4 + MK-7 + K1 blend) + 1,000mcg iodine per capsule - active D3 dose plus broad K2 coverage and thyroid support
Life Extension above-average quality standards. Third-party tested. GMP facility.
$0.31/day - reasonable for a multi-form K blend with D3 and iodine in a single capsule
Both K2 forms (MK-4 and MK-7) plus K1 disclosed with amounts. D3 form confirmed. Iodine source listed.
Life Extension's current combined D+K product. Broad K coverage (MK-4 + MK-7 + K1) paired with 5,000 IU D3 and iodine. A formulation-forward choice if you also want thyroid support in one capsule.
How We Compared These Products
Every product in our database is scored on four equally-weighted pillars: dosing accuracy and form quality, purity verification (third-party testing), cost per clinically effective dose (not cost per pill), and label transparency. Each pillar is worth 25 points for a total of 100.
Cost per effective dose is calculated using the clinically studied dose from published research, not the manufacturer's suggested serving. If a product requires multiple servings to reach the dose used in clinical trials, that cost is reflected in the value score.
For a full explanation of our scoring methodology, see our methodology page. Prices were last checked on the dates listed for each product and may have changed.
Frequently Asked Questions
Is Pure Encapsulations or Life Extension D3+K2 better?
They are close: Pure Encapsulations scores slightly higher on our rubric (92 vs 90 on our 0-100 execution score) with a clean hypoallergenic D3 + MK-7 formula, and both cost about $0.30 per day. Life Extension's edge is a broader K complex (MK-4, MK-7, and K1) plus iodine. Choose Pure Encapsulations for a focused, hypoallergenic formula, Life Extension for the wider spread of K forms.
Does the K2 form (MK-7 vs MK-4) matter?
Somewhat. MK-7 has a longer half-life in the body, so it stays active longer from a single daily dose, which is why most D3+K2 products use it. MK-4 acts more quickly but clears faster and is typically studied at higher doses. Pure Encapsulations uses MK-7; Life Extension includes both MK-4 and MK-7. For once-daily use, MK-7 is the more convenient form, but a formula with both covers more bases.
More Vitamin D3 + K2 Comparisons
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FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before starting any supplement regimen.