Sleep & Relaxation
If you're lying awake at 2am wondering what actually helps, start here. Melatonin, magnesium glycinate, L-theanine, GABA, 5-HTP, and sleep support formulas.
Magnesium Glycinate
Sleep quality, muscle relaxation, anxiety reduction, blood pressure support
Melatonin
Sleep onset latency reduction, circadian rhythm regulation, jet lag recovery
5-HTP (5-Hydroxytryptophan)
A serotonin precursor derived from Griffonia simplicifolia seeds that may improve sleep quality, support mood, and promote satiety by increasing central serotonin synthesis.
L-Theanine
Reduces subjective stress and anxiety while promoting relaxed focus without sedation
GABA (Gamma-Aminobutyric Acid)
Stress reduction, relaxation, and sleep support (mechanism disputed)
Glycine
Improved subjective sleep quality, reduced sleep onset latency, and reduced next-day fatigue when taken before bed
Inositol
PCOS metabolic and ovulatory support, gestational diabetes prevention, anxiety and panic disorder
Tart Cherry
Exercise recovery (DOMS, strength, oxidative stress) and modest sleep quality improvements
Lemon Balm
Mild stress and anxiety reduction, sleep onset support, acute calmness and cognitive performance
Reishi Mushroom
Immune modulation and adaptogenic support; modest evidence for cancer-adjuvant immune markers, fatigue, and quality of life
Apigenin
Plant flavone from chamomile and parsley, studied in cells and rodents for relaxation, NAD+/CD38 modulation, and longevity; no high-quality human RCTs on the standalone supplement
Holy Basil (Tulsi)
Stress response support, mood balance, and sleep quality through Ayurvedic adaptogen pathways; secondary signal for blood-glucose regulation
Kava
Short-term relaxation and occasional anxious feelings; traditionally used as an evening calmative
Saffron
Mood support, mild low-mood and stress, sleep quality, and PMS-related symptoms
Valerian Root
Supports subjective sleep quality and relaxation with nightly use over 2-4 weeks; modest objective effects
SAMe (S-Adenosylmethionine)
A methyl donor synthesized in the body from methionine and ATP that supports a positive mood, joint comfort, and liver function via methylation, transsulfuration, and aminopropylation pathways.
Schisandra
Traditional adaptogen used for stress resilience, mental performance under fatigue, and liver support; modern human RCT base is thin compared to other adaptogens.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products discussed on this page are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before starting any supplement regimen.