Joint & Bone Health

For stiff knees, aging joints, or keeping bones strong as you get older. Glucosamine, chondroitin, MSM, collagen, boswellia, and bone support supplements.

Collagen Peptides

Collagen Peptides

Skin elasticity, joint cartilage support, and muscle mass maintenance in older adults

Mixed Evidence13 products
Boswellia Serrata

Boswellia Serrata

Reduces joint pain and improves physical function in osteoarthritis through inhibition of 5-LOX inflammatory pathways, with emerging evidence for inflammatory bowel disease.

Mixed Evidence10 products
Glucosamine Sulfate

Glucosamine Sulfate

Reduction in joint pain and stiffness associated with knee osteoarthritis, with potential to slow structural disease progression

Mixed Evidence10 products
MSM (Methylsulfonylmethane)

MSM (Methylsulfonylmethane)

Joint pain relief, osteoarthritis symptom management, exercise recovery

Mixed Evidence10 products
Chondroitin Sulfate

Chondroitin Sulfate

Modest reduction in knee osteoarthritis pain and potential slowing of cartilage loss, though evidence is contested

Mixed Evidence10 products
Boron

Boron

Bone mineral metabolism, modest free testosterone elevation in men, joint and inflammation markers

Weak Evidence9 products
Tart Cherry

Tart Cherry

Exercise recovery (DOMS, strength, oxidative stress) and modest sleep quality improvements

Mixed Evidence10 products
Palmitoylethanolamide (PEA)

Palmitoylethanolamide (PEA)

Studied for nerve discomfort, low back pain with sciatic involvement, and general pain comfort via PPAR-alpha activation and modulation of mast cell and glial cell signaling.

Mixed Evidence8 products
Bromelain

Bromelain

Supports post-surgical recovery, post-exercise soreness, sinus and nasal comfort, and supplemental joint comfort in osteoarthritis adjunct use

Mixed Evidence9 products
N-Acetyl Glucosamine (NAG)

N-Acetyl Glucosamine (NAG)

Substrate for glycosaminoglycan, hyaluronic acid, and mucin synthesis; preliminary signals for joint comfort, gut barrier support, and skin hyperpigmentation (topical)

Weak Evidence8 products
SAMe (S-Adenosylmethionine)

SAMe (S-Adenosylmethionine)

A methyl donor synthesized in the body from methionine and ATP that supports a positive mood, joint comfort, and liver function via methylation, transsulfuration, and aminopropylation pathways.

Likely Effective8 products
Ginger (Zingiber officinale, rhizome extract)

Ginger (Zingiber officinale, rhizome extract)

Supports digestive comfort and a normal nausea response; modest joint comfort support

Likely Effective8 products

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products discussed on this page are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before starting any supplement regimen.